Massive Empyema Associated With Transient Hypogammaglobulinemia of Infancy and IgA Deficiency.
10.3346/jkms.2009.24.2.357
- Author:
Kuhn PARK
1
;
Kyung Yil LEE
;
Mi Hee LEE
;
Joon Sung LEE
;
Ji Chang KIM
Author Information
1. Department of Thoracic and Cadiovascular Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Transient Hypogammaglobulinemia of Infancy;
IgA Immunodeficiency;
Empyema;
Streptococcus pneumoniae
- MeSH:
Agammaglobulinemia/complications/*diagnosis/immunology;
Anti-Bacterial Agents/therapeutic use;
Ceftriaxone/therapeutic use;
Drug Resistance, Bacterial;
Empyema, Pleural/*diagnosis/etiology/radiography;
Female;
Humans;
IgA Deficiency/*diagnosis/immunology;
Immunoglobulin A/blood;
Immunoglobulin G/blood;
Infant;
Staphylococcal Infections/*diagnosis/drug therapy/microbiology;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2009;24(2):357-359
- CountryRepublic of Korea
- Language:English
-
Abstract:
Transient hypogammaglobulinemia of infancy (THI) is originally defined as a physiological maturation defect of immunoglobulin G (IgG) production that occurs at 3-6 months of age and lasts until 18 to 36 months of age. We report here on a 22-month-old child with THI and IgA deficiency, who had massive pneumococcal empyema. Her depressed IgG level returned to normal within 6 months, but IgA level was still low at 6 yr of age. Although THI is an age-dependent and self-limiting disorder, severe infection that includes an atypical presentation of an infection may occur in some patients and this requires evaluation with immunologic study.
