A Case of Incidental Epidermolytic Hyperkeratosis Occurring Normal Looking Skin Adjacent to Folliculitic Papules: In Veterans Who Participated in Vietnam War.
10.5021/ad.2003.15.2.82
- Author:
Se Won LEE
;
Seung Hyun CHUN
;
Eung Ho CHOI
;
Sung Ku AHN
- Publication Type:Case Report
- Keywords:
Incidental epidermolytic hyperkeratosis;
2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD:Agent Orange)
- MeSH:
Cicatrix;
Humans;
Hyperkeratosis, Epidermolytic*;
Keratinocytes;
Middle Aged;
Peripheral Nervous System Diseases;
Skin*;
Tetrachlorodibenzodioxin;
Veterans*;
Vietnam*
- From:Annals of Dermatology
2003;15(2):82-84
- CountryRepublic of Korea
- Language:English
-
Abstract:
On histological examination, an epidermolytic hyperkeratosis was observed adjacent to follicular papules on the back of a 53-year-old man. It has been reported that incidental epidermolytic hyperkeratosis occur either within various lesion (epidermal neoplasm, melanocytic neoplasm, scars, and inflammatory conditions) or in the normal skin adjacent to the lesion. This patient participated in the Vietnam War for 2 years, and had had contact with defoliants. He was treated for multiple peripheral neuropathies and cerebral infarcts. In keratinocytes, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD; Agent Orange) contained in defoliating agents is associated with altered patterns of keratinocyte differentiation. So, as a cause of incidental epidermolytic hyperkeratosis, defoliant contact could be suspected.
