Isolated splenic metastasis from colorectal carcinoma: a case report.
10.3346/jkms.2000.15.3.355
- Author:
Jin Cheon KIM
1
;
Choon Sik JEONG
;
Hee Cheol KIM
;
Chang Sik YU
;
Gyeong Hoon KANG
;
Moon Gyu LEE
Author Information
1. Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. jckim@www.amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Colorectal Neoplasms;
Spleen;
Neoplasm Metastasis;
Carcinoembryonic Antigen
- MeSH:
Adenocarcinoma/surgery;
Adenocarcinoma/secondary*;
Adenocarcinoma/pathology;
Adenocarcinoma/blood;
Aged;
Carcinoembryonic Antigen/blood;
Case Report;
Colorectal Neoplasms/surgery;
Colorectal Neoplasms/pathology*;
Colorectal Neoplasms/blood;
Human;
Male;
Splenic Neoplasms/surgery;
Splenic Neoplasms/secondary*;
Splenic Neoplasms/blood;
Tomography Scanners, X-Ray Computed
- From:Journal of Korean Medical Science
2000;15(3):355-358
- CountryRepublic of Korea
- Language:English
-
Abstract:
Isolated splenic metastasis arising from colorectal carcinoma is very rare and there has been only 6 cases reported in the English literature. A new case is esented, and its possible pathogenesis was considered with previously reported ses. A 65-year-old male patient had received a right hemicolectomy for cending colon cancer 36 months earlier. He was followed up regularly with rial measurement of serum carcinoembryonic antigen (CEA). Rising serum CEA was scovered from 33 months postoperatively and CT revealed an isolated splenic tastasis. He therefore underwent splenectomy, which was proven to be a tastatic adenocarcinoma with similar histological feature to the original mor. As all reported cases showed elevated serum CEA at the time of tastasis, isolated splenic metastasis might be associated with CEA in regard its biological functions of immunosuppression and adhesion.
