A Primary Large Cell Neuroendocrine Carcinoma of the Urinary Bladder in a 19-year-old Man.
10.4111/kju.2008.49.7.647
- Author:
Whi An KWON
1
;
Yun Sok HA
;
Ok Jun LEE
;
Yong June KIM
;
Seok Joong YUN
;
Sang Cheol LEE
;
Wun Jae KIM
Author Information
1. Departments of Urology, Chungbuk National University College of Medicine, Cheongju, Korea. wjkim@ chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma;
large cell;
Neuroendocrine carcinoma;
Urinary bladder
- MeSH:
Carcinoma, Neuroendocrine;
Cystectomy;
Hematuria;
Humans;
Recurrence;
Synaptophysin;
Urinary Bladder;
Urinary Bladder Neoplasms;
Young Adult
- From:Korean Journal of Urology
2008;49(7):647-649
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary large cell neuroendocrine carcinomas of the urinary bladder are extremely rare. To date, only six cases of large cell neuroendocrine carcinoma have been reported. We present a case of a 19-year-old man who presented with gross hematuria and who was subsequently found to have a solitary tumor on the dome of the urinary bladder. The patient underwent transurethral resection of the bladder tumor for histological confirmation. A diagnosis of large cell neuroendocrine carcinoma was made based upon immunohistochemical reactivity for synaptophysin and CD56. Based on the pathologic diagnosis, he subsequently had a partial cystectomy. Histologically, the tumor penetrated the perivesical fat. It has now been 6 months since the surgery, and the patient is preparing to receive his 5th cycle of chemotherapy. There is no evidence of tumor recurrence or metastasis.
