Two Cases of Cutaneous Leishmaniasis Treated with Itraconazole.
10.5021/ad.1992.4.2.91
- Author:
Byoung Chan PARK
;
Hee Jae CHAE
;
Jong Yuk YI
;
Baik Kee CHO
;
Won HOUH
;
Dong Jin KIM
;
Won Young CHOI
- Publication Type:Case Report
- Keywords:
Cutaneous leishmaniasis;
Itraconazole
- MeSH:
Adult;
Biopsy;
Culture Media;
Extremities;
Female;
Humans;
Itraconazole*;
Leishmania;
Leishmaniasis, Cutaneous*;
Neck;
Skin;
Young Adult
- From:Annals of Dermatology
1992;4(2):91-94
- CountryRepublic of Korea
- Language:English
-
Abstract:
Two patients with cutaneous leishmaniasis were treated with itraconazole. One patient was a 24-year-old man who had several erythematous papulonodules on the extremities for 1 month, which revealed cutaneous leishmaniasis, histopathologically. He was treated with itraconazole (200 mg/day) for 2 months. After treatment he showed clinical healing and the biopsy specimens no longer showed leishmania organisms. The other patient was a 27-year-old female who had several erythematous papulonodules on the face and neck for 3 months. The skin lesions revealed leishmania organisms in the tissue sections and culture media. She was also treated with itraconazole (200 mg/day) for 2 months. After treatment she also showed satisfying clinical healing and the biopsy specimens revealed no leishmania organisms. No specific side effects were encountered in both patients during the treatment. From these results, itraconazole is considered to be one of the promising anti-leishmanial drugs.
