A Case of Fulminant Type 1 Diabetes Mellitus with Peripheral Neuropathy in a Korean Child.
- Author:
Min Sun KIM
1
;
Ka Young YU
;
Soo Yeon LEE
;
Sun Young KIM
;
Sun Jun KIM
;
Pyoung Han HWANG
;
Dae Yeol LEE
Author Information
1. Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. leedy@chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Diabetes Mellitus;
Type 1;
Diabetic Neuropathy;
Child
- MeSH:
Adolescent;
Autoantibodies;
Autoimmunity;
Blood Glucose;
Child;
Diabetes Mellitus;
Diabetes Mellitus, Type 1;
Diabetic Neuropathies;
Humans;
Insulin;
Insulin-Secreting Cells;
Japan;
Korea;
Peripheral Nervous System Diseases;
Reference Values
- From:Journal of Korean Society of Pediatric Endocrinology
2009;14(1):82-84
- CountryRepublic of Korea
- Language:English
-
Abstract:
Type 1 diabetes is an insulin-deficient status due to severe destruction of pancreatic beta cells, and is classified into two subtypes, type 1A and type 1B. Type 1A diabetes is autoimmune and type 1B is idiopathic diabetes. Recently fulminant type 1 diabetes has been identified as a new subtype of idiopathic diabetes. It develops rapidly without any evidence of autoimmunity. This subtype of type 1 diabetes was firstly introduced by Imagawa et al. in 2000, and exclusively reported in Japan. Nonetheless, there has been no case reported in Korea till now. Here, we report a case of fulminant type 1 diabetes in 14-year-old girl. She had acute symptoms for short duration, negative islet-related autoantibodies, elevated serum levels of pancreatic exocrine enzymes (amylase, lipase), high blood glucose level and peripheral neuropathy. But HbA1c level was in normal range. Treatment with insulin was successful, acute symptoms were improved and abnormal laboratory data normalized. Her recent HbA1c level showed only a mild elevation.
