Correlation between Proximal Abdominal Aortic Stiffness Measured by Ultrasound and Brachial-Ankle Pulse Wave Velocity.
10.4070/kcj.2013.43.6.391
- Author:
Young Hyo LIM
1
;
Rentsendorj ENKHDORJ
;
Bae Keun KIM
;
Soon Gil KIM
;
Jeong Hyun KIM
;
Jinho SHIN
Author Information
1. Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. jhs2003@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Abdominal aorta;
Arteriosclerosis;
Blood pressure;
Elastic modulus;
Pulse wave velocity
- MeSH:
Aorta, Abdominal;
Arteriosclerosis;
Blood Pressure;
Body Mass Index;
Elastic Modulus;
Female;
Heart Rate;
Humans;
Hypertension;
Multivariate Analysis;
Pulse Wave Analysis;
Sprains and Strains;
Vascular Stiffness
- From:Korean Circulation Journal
2013;43(6):391-399
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The proximal portion of the abdominal aorta (AA) is characterized by minimal arteriosclerosis compared with other aortic segments. To assess the clinical usefulness of this characteristic, the correlation between ultrasonographically measured proximal AA stiffness and brachial-ankle pulse wave velocity (baPWV) was examined. SUBJECTS AND METHODS: 285 subjects were analyzed, half with hypertension and half with normal blood pressure. Proximal AA was examined using ultrasonography; strain, distensibility, elastic modulus, and the stiffness index were determined. After adjustment for age, gender, body mass index (BMI), systolic blood pressure (SBP), and heart rate, the relationships between baPWV and all these parameters were tested. RESULTS: The mean age of the study subjects was 58.1+/-12.8 years and the mean BMI was 24.3+/-3.8 kg/cm2. 58.9% of the subjects were female. 42.8% were hypertensive subjects. Among the hypertensive subjects, 56.0% were taking antihypertensive medication. Adjusted partial correlation coefficients for the relationship between baPWV with strain, distensibility, elastic modulus, and the stiffness index of the proximal AA were -0.203 (p=0.01), -0.121 (p=0.129), 0.304 (p=0.0001), and 0.299 (p=0.0001), respectively, in normotensive subjects. In the multivariate analyses, such correlations were observed mainly in the normotensive group, whereas there was no association among hypertensive subjects regardless of antihypertensive medication status. CONCLUSION: baPWV is moderately correlated with the stiffness parameters for the proximal AA, mainly in normotensive subjects.
