Acute Myeloid Leukemia Presenting as Obstructive Jaundice Caused by Granulocytic Sarcoma.
- Author:
Joo Young LEE
1
;
Wan Suk LEE
;
Min Kyu JUNG
;
Seong Woo JEON
;
Chang Min CHO
;
Won Young TAK
;
Young Oh KWEON
;
Sung Kook KIM
;
Yong Hwan CHOI
;
Jong Gwang KIM
;
Sang Kyun SOHN
Author Information
1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea. whckd@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Leukemia, Myelocytic, Acute;
Jaundice, Obstructive;
Bile ducts;
Retrograde cholangiopancreatography, Endoscopic
- MeSH:
Bile Ducts;
Bile Ducts, Intrahepatic;
Bilirubin;
Bone Marrow;
Cholangiopancreatography, Endoscopic Retrograde;
Cholangiopancreatography, Magnetic Resonance;
Cytarabine;
Dilatation;
Drainage;
Drug Therapy;
Humans;
Idarubicin;
Induction Chemotherapy;
Jaundice;
Jaundice, Obstructive*;
Leukemia, Myeloid, Acute*;
Liver Function Tests;
Remission Induction;
Sarcoma, Myeloid*;
Weight Loss;
Young Adult
- From:Gut and Liver
2007;1(2):182-185
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a rare case of granulocytic sarcoma infiltrating the bile duct in a patient with acute myeloid leukemia. A 23-year-old man presented with jaundice and weight loss. A peripheral blood smear revealed blast cells, and the results of an examination of bone marrow aspirate were consistent with acute myeloid leukemia. The bilirubin level increased gradually after induction chemotherapy with cytarabine. Magnetic resonance cholangiopancreatography (MRCP) revealed dilatation of the intrahepatic bile ducts and smooth tapering off at the level of the common hepatic bile duct. Endoscopic retrograde cholangiopancreatography (ERCP) also revealed diffuse narrowing of the proximal common hepatic bile duct. Obstructive jaundice resolved after endoscopic nasobiliary drainage. Remission induction chemotherapy with cytarabine and idarubicin was administered, and the patient remained complete hematological remission with normal liver function tests.
