Cutaneous Sarcoidosis Clinically Mimicking Necrobiosis Lipoidica in a Patient with Systemic Sarcoidosis.

Author: Takahito CHIBA ¹ ; Masakazu TAKAHARA ; Takeshi NAKAHARA ; Shuji FUKAGAWA ; Kenjiro TAKEI ; Asuka SHONO ; Hiromaro KIRYU ; Yoichi MOROI ; Masutaka FURUE
Author Information

1. Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. allheart@dermatol.med.kyushu-u.ac.jp
Publication Type:Case Report
Keywords: Granuloma; Necrobiosis lipoidica; Sarcoidosis
MeSH: Aged; Biopsy; Dermis; Female; Granuloma; Granuloma Annulare; Humans; Hydrazines; Leg; Necrobiosis Lipoidica; Necrobiotic Disorders; Sarcoidosis
From:Annals of Dermatology 2012;24(1):74-76
CountryRepublic of Korea
Language:English
Abstract: A 70-year-old woman with an 8-year history of systemic sarcoidosis developed round, red-brown eruptions, with central atrophic lesions on her lower legs. The features of the biopsy specimen resembled those of necrobiosis lipoidica (NL), but although necrobiosis was present there were well-formed non-necrotizing granulomas in the dermis. The histological diagnosis was cutaneous sarcoidosis. Systemic sarcoidosis presenting with NL has rarely been reported. The histological features of cutaneous sarcoidosis sometimes mimic those of other granulomatous diseases, including NL and granuloma annulare, which are difficult to distinguish. We discuss the novel association between sarcoidosis and other granulomatous diseases.