Histologic Grading by Modified MDAH System and Prognosis of Prostatic Carcinoma.
- Author:
Kyoung Suk CHAE
1
;
Byung Kap MIN
Author Information
1. Department of Urology, Chonnam University, Medical School, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
prostatic carcinoma;
prognosis;
MDAH system
- MeSH:
Adenocarcinoma;
Humans;
Jeollanam-do;
Prognosis*;
Prostatic Neoplasms;
Retrospective Studies;
Texas
- From:Korean Journal of Urology
1987;28(3):363-368
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since the behavior of malignant cells can be predicted by their histologic appearance, various attempts have been made to develop a uniform grading system for prostatic cancer. The system employed at the University of Texas M.D. Anderson Hospital(MDAH system) is based simply on assessment of percentage of gland formation in the tumor. Herein, using the modified MDAH system, histologic grading and prognosis were retrospectively reviewed in 35 patients with prostatic adenocarcinoma managed at Chonnam University Hospital between l997 and 1984. The following results were obtained. 1. The average age of all the patients was 70.1 years, with a range of 25 to 85 years. 2. In 35 patients, the modified MDAH system identified 6 patients (l7%) as Grade 1, 15(43%) as Grade 2-3, and 14 (40%) as Grade 4. There were a 83% 3-year survival for Grade 1 patients, a 69% 3-year survival for Grade 2-3 patients, and a 17% 3-year survival for Grade 4 patients. 3. Of 15 patients with clinical stage D, 2 had Grade 1, 6 had Grade 2-3, and 7 had Grade 4.There were a 100 % 3-year survival for Grade 1 patients, a 50% 3-year survival for Grade 2-3patients, and a 14% 3-year survival for Grade 4 patients.
