The Recent Status of Multidrug- and Extensively Drug-Resistant Tuberculosis in Korea.
10.4046/trd.2010.68.3.146
- Author:
Sun Young KIM
1
;
Hee Jin KIM
;
Chang Ki KIM
;
Hye Ryung YOON
;
Hye Gyung BAE
;
Sun Hwa LEE
;
Nackmoon SUNG
;
Dae Yeon KIM
;
Gang Young LEE
;
Young Soo CHO
;
Sang Do LEE
;
Woo Sung KIM
;
Dong Soon KIM
;
Tae Sun SHIM
Author Information
1. Division of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. shimts@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Tuberculosis, Multidrug-Resistant;
Extensively Drug-Resistant Tuberculosis;
Microbial Sensitivity Tests;
Korea
- MeSH:
Extensively Drug-Resistant Tuberculosis;
Humans;
Incidence;
Korea;
Microbial Sensitivity Tests;
Mycobacterium tuberculosis;
Tuberculosis, Multidrug-Resistant
- From:Tuberculosis and Respiratory Diseases
2010;68(3):146-154
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has become a serious worldwide problem. However, there is insufficient data regarding the current status of MDR-TB and XDR-TB in Korea. This study examined the recent status of MDR- and XDR-TB using the data from 7 laboratories, in which almost all drug susceptibility tests (DST) for Mycobacterium tuberculosis were performed. METHODS: The patients' identification data and DST results were collected from all 7 laboratories from 2001 to 2006 and the number of patients with MDR-TB and XDR-TB were calculated. RESULTS: The number of DSTs was 140,638 for 6 years with an increasing incidence each year (p<0.001). The number of DST with MDR results was 18,510 and personal identifying information was obtained in 16,640 (89.9%) tests. The number of MDR-TB patients from 2001 to 2006 was 2,329, 2,496, 2,374, 2,300, 2,354, and 2,178, respectively, when counting the duplications in a year as one patient. The number of MDR-TB patients when counting the duplications in 6 years as one patient was 2,281, 1,977, 1,620, 1,446, 1,512, and 1,373, respectively. When the same method was adopted, the number of XDR-TB patients was 191, 238, 282, 260, 272, and 264, respectively, and 189, 150, 130, 90, 122, and 110 patients, respectively. CONCLUSION: Despite the national efforts to control TB, there are still a large number of MDR- and XDR-TB patients in Korea.
