Evaluation of the Changes of Coagulation-Fibrinolysis System during Transurethral Resection of the Prostate by Thromboelastography.
- Author:
Tae Hun KIM
1
;
Dae Yul YANG
;
Sung Yong KIM
;
Hayoung KIM
;
Hong Seong YOO
;
Hyun CHOI
;
Young Joon YOON
Author Information
1. Hallym University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Coagulation-fibrinolysis system;
TURP;
Thromboelastography
- MeSH:
Fibrinolysis;
Humans;
Platelet Count;
Prostate*;
Prostatic Hyperplasia;
Reaction Time;
Reference Values;
Thrombelastography*;
Transurethral Resection of Prostate
- From:Korean Journal of Urology
1997;38(11):1217-1222
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We studied intraoperative changes of transurethral resection of the prostate in blood coagulation-fibrinolysis system by thromboelastography (TEG) in 31 patients with benign prostatic hyperplasia. As TEG parameters reaction time (R), clot formation time (K), maximum amplitude (MA), coagulation time (R+K), clot lysis index after 60 minutes (Ly60) were measured. The coagulability was evaluated by R and R+K, the absolute strength of clot by MA, and fibrinolysis by Ly60. Coagulation time (R+K) was shortened in patients with decreased platelet count under 30,000 u/L (p<0.05), irrigating fluid volume over 20,000 ml (p<0.05) and had a tendency of shortening in patient with resection time over 50minutes (p=0.078). MA had a tendency of increasing but significant contributing factor was not detected. The mean value of Ly60 was increased significantly but the change was in normal range. Irrigating fluid volume (r=-0.407, p<0.05) and resection time (r=-0.456, p<0.05) showed negative correlation significantly with the change of R + K. There was no significant correlation between resected prostatic weight and TEG parameters. We concluded that coagulability is increased during TURP suggesting a possible role in postoperative clot retention, but the risk of fibrinolysis is not increased in patients with normal coagulation-fibrinolysis system.
