Sarcomatoid Carcinoma of the Urinary Bladder: A Clinicopathological Study of 4 Cases and a Review of the Literature.
10.4111/kju.2010.51.10.724
- Author:
Konstantinos STAMATIOU
1
;
Nikolaos GALARIOTIS
;
Ioannis MICHAILIDIS
;
Nerantzoula PETRAKOPOULOU
;
Helen MOUSTOU
;
Adamantia ZIZI-SERMPETZOGLOU
Author Information
1. Department of Urology, Tzaneio General Hospital of Pireas, Pireas, Greece. stamatiouk@gmail.com
- Publication Type:Case Report
- Keywords:
Transitional cell carcinoma;
Urinary bladder neoplasms
- MeSH:
Carcinoma, Transitional Cell;
Female;
Humans;
Male;
Urinary Bladder;
Urinary Bladder Neoplasms
- From:Korean Journal of Urology
2010;51(10):724-728
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sarcomatoid carcinoma (SC) of urinary bladder is a rare tumor exhibiting aggressive behavior. Here we are reviewing the pathologic and clinical characteristics of 4 consecutive cases of this rare tumor. Three out of 4 patients were males and one female. The median age was 72.8 years (range, 60-79 years). Patients underwent transurethral resection of bladder tumor and the diagnosis of bladder SC was established on the pathologic examination of the resected bladder tissue. Despite treatment all patients died within 22 months of the diagnosis of SC. SC of the bladder are true biphasic malignant neoplasm exhibiting morphologic and immunohistochemical evidence of epithelial and mesenchymal differentiation with the presence or absence of heterologous elements. The aggressive of the tumor precludes radical therapy whenever possible, since adjuvant therapy seems to have little effect.
