The Management of Heparin-induced Thrombocytopenia with Thrombosis That Developed after Aortic Dissection Surgery.
- Author:
JaeBum KIM
1
;
Nam Hee PARK
;
Sae Young CHOI
Author Information
1. Department of Thoracic and Cardiovascular Surgery, College of Medicine, Keimyung University, Korea. nhpark@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Heparin;
Thrombocytopenia;
Thrombosis
- MeSH:
Amputation;
Antibodies;
Drug Toxicity;
Extremities;
Heparin;
Humans;
Immunoglobulin G;
Myocardial Infarction;
Pipecolic Acids;
Stroke;
Thrombocytopenia;
Thrombosis
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2010;43(5):538-541
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Heparin-induced thrombocytopenia (HIT) is a clinicopathologic condition and adverse drug reaction caused by immunoglobulin G (IgG) antibodies directed against the heparin-platelet factor 4 complex. HIT with thrombosis (HITT) could lead to limb amputation, stroke, myocardial infarction, and death. We report on the successful management of a HITT patient with argatroban therapy.