Three Cases of Secondary Fungal Infection in Herpes Simplex Keratitis.
10.3341/jkos.2010.51.9.1271
- Author:
Gui Hyeong MUN
1
;
Yeoung Geol PARK
;
In Cheon YOU
;
Kyung Chul YOON
Author Information
1. Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. kcyoon@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Fungus;
Herpetic keratitis;
Secondary infection
- MeSH:
Antifungal Agents;
Antiviral Agents;
Candida albicans;
Coinfection;
Eye;
Fungi;
Fusarium;
Herpes Simplex;
Humans;
Hyphae;
Keratitis;
Keratitis, Herpetic;
Methylmethacrylates;
Polystyrenes;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
2010;51(9):1271-1275
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report several cases of secondary infection by fungus in herpes simplex keratitis. CASE SUMMARY: A retrospective chart review was performed on 3 eyes of 3 patients who were without improvement and diagnosed with fungal keratitis by smear and culture on prior presentation with herpetic keratitis. Two cases were diagnosed with fungal keratitis, based on the results of culture. Fungal keratitis by Candida albicans was improved with antifungal agents, but a case caused by Fusarium species was more aggravated, regardless of antifungal agents. One case was improved by antifungal medications, which was diagnosed with fungal keratitis by the fungal hyphae manifestation on KOH preparation. CONCLUSIONS: Secondary microbial infection should be considered, when the lesion had no improvement with antiviral agents in herpetic keratitis.