A clinical study of borderline malignant tumors of the ovary.
- Author:
Nan Hee JEONG
1
;
Yun ah KIM
;
Sang Geun JEONG
;
Chan LEE
;
Tak KIM
;
Hai Joong KIM
;
Kyu Wan LEE
;
Nak Woo LEE
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Korea University, Ansan, Korea. nwlee@korea.ac.kr
- Publication Type:Original Article
- Keywords:
Borderline ovarian tumor;
Surgical staging;
Clinical study;
Prognosis
- MeSH:
Brenner Tumor;
Drug Therapy;
Female;
Follow-Up Studies;
Humans;
Mucins;
Ovary*;
Prognosis;
Recurrence;
Retrospective Studies;
Survival Rate
- From:Korean Journal of Gynecologic Oncology
2007;18(1):39-47
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The purpose of this study was to evaluate the clinical and histopathological features, and to find relationship between treatment modality and prognosis of borderline ovarian tumors. METHODS: Ninety-three cases of borderline ovarian tumors that had been treated were reviewed retrospectively. RESULTS: Histologic types of this study group composed of 67 cases of mucinous borderline tumor, 23 cases of serous borderline tumor, 2 cases of mixed type, and 1 case of Brenner tumor. The mean age was 41.6 years (range 14 to 83), and 41 (44.1%) patients were nullipara. The most common chief complaint was palpable mass (39.8%) and asymptomatic cases were presented in 23 patients (24.7%). The cases of elevated serum CA125 (< or =35 IU/ml) were 25.8% in mucinous type and 61.9% in serous type. Surgical staging was completed in 57 cases and other 36 cases were incompletely staged. 45 cases were managed by conservative surgery. There were 4 cases with recurrence, and all of them were related to conservative surgery. Chemotherapy was given to 40 cases. Mean follow-up period was 27.3 months. One patient expired during follow-up, and overall 5-year survival rate was 95.2%. CONCLUSION: Borderline ovarian tumors have a good prognosis. But recurrence rate was high in conservative surgery. In conclusion, careful preoperative evaluations, complete surgical exploration and long-term follow-up after treatment are needed.
