Sudden rapid growth of an aggressive angiomyxoma after taking pomegranate seeds oil.
- Author:
Mi Kyoung KIM
1
;
Eun Kyoung SHIN
;
In Suk SHIM
;
Sun Ok LEE
;
Woong JU
;
Seung Cheol KIM
;
Sun Hee SUNG
;
Woon Sup HAN
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, Korea. onco@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Angiomyxoma;
Pomegranate seeds oil;
Vulva
- MeSH:
Diagnosis;
Estrogens;
Female;
Gonadotropin-Releasing Hormone;
Humans;
Middle Aged;
Myxoma*;
Perineum;
Punicaceae*;
Vulva;
Prunus dulcis
- From:Korean Journal of Gynecologic Oncology
2007;18(1):58-61
- CountryRepublic of Korea
- Language:English
-
Abstract:
Aggressive angiomyxoma (AA) is a rare soft tissue tumor of undetermined etiology that occurs mainly in the female vulva and perineum. It has been demonstrated to increase in size under the estrogenic stimulation and shown to respond to treatment with a GnRH agonist. A 47-year-old woman was presented with a large vulvar mass. The mass had grown slowly before she took pomegranate seeds oil on a regular basis for a year, which is known to contain natural estrogen for a year. The almond-sized mass enlarged into a fetal head-sized one in a year. Our case is implying that external administration of estrogenic substance may be a contributory factor to the sudden accelerated growth of AA. Although the past medical history in this case relies on an unverified observation by the patient alone, the unique clinical course and impressive gross appearance of AA may help clinicians with diagnosis in practice.
