A randomized controlled clinical study of periodontal tissue regeneration using an extracellular matrix-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects.
10.5051/jpis.2017.47.6.363
- Author:
Sulhee KIM
1
;
Hyeyoon CHANG
;
Jin wook HWANG
;
Sungtae KIM
;
Ki Tae KOO
;
Tae Il KIM
;
Yang Jo SEOL
;
Yong Moo LEE
;
Young KU
;
Jong Ho LEE
;
In Chul RHYU
Author Information
1. Department of Periodontology, Seoul National University School of Dentistry, Seoul, Korea. kst72@snu.ac.kr
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Bone regeneration;
Bone substitutes;
Cone-beam computed tomography;
Guided tissue regeneration;
Three-dimensional imaging
- MeSH:
Bone and Bones;
Bone Regeneration;
Bone Substitutes;
Clinical Study*;
Collagen*;
Cone-Beam Computed Tomography;
Extracellular Matrix;
Guided Tissue Regeneration;
Imaging, Three-Dimensional;
Membranes*;
Regeneration*;
Tooth;
Transplants*
- From:Journal of Periodontal & Implant Science
2017;47(6):363-371
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to investigate the feasibility of regenerative therapy with a collagenated bone graft and resorbable membrane in intrabony defects, and to evaluate the effects of the novel extracellular matrix (ECM)-based membrane clinically and radiologically. METHODS: Periodontal tissue regeneration procedure was performed using an ECM-based resorbable membrane in combination with a collagenated bovine bone graft in intrabony defects around the teeth and implants. A novel extracellular matrix membrane (NEM) and a widely-used membrane (WEM) were randomly applied to the test group and the control group, respectively. Cone-beam computed tomography images were obtained on the day of surgery and 6 months after the procedure. Alginate impressions were taken and plaster models were made 1 week and 6 months postoperatively. RESULTS: The quantity of bone tissue, the dimensional changes of the surgically treated intrabony defects, and the changes in width and height below the grafted bone substitutes showed no significant difference between the test and control groups at the 6-month examination. CONCLUSIONS: The use of NEM for periodontal regeneration with a collagenated bovine bone graft showed similar clinical and radiologic results to those obtained using WEM.
