Coexistence of IgA Nephropathy and Post-infectious Glomerulonephritis.
- Author:
Jeong Rok LEE
1
;
Young Shin SHIN
;
Seung Woo LEE
;
Hyun Chul CHOI
;
Hyung Wook KIM
;
Cheol Whee PARK
;
Young Jin CHOI
;
Yoon Sik CHANG
;
Byung Kee BANG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. ysshincmc@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Ig A nephropathy;
Postinfectious glomerulonephritis;
Coexistence
- MeSH:
Adult;
Biopsy;
Edema;
Glomerulonephritis*;
Glomerulonephritis, IGA*;
Hematuria;
Humans;
Hypertension;
Immunoglobulin A*;
Mesangial Cells;
Microscopy, Electron;
Microscopy, Fluorescence;
Nephrotic Syndrome;
Neutrophils;
Prognosis;
Proteinuria;
Respiratory Tract Infections
- From:Korean Journal of Nephrology
2003;22(6):773-776
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 33-year-old man was admitted with macroscopic hematuria and systemic edema appearing after an acute upper respiratory tract infection. On admission, hypertension, nephrotic syndrome were evident together with a decreased renal function. Renal biopsy showed markedly increased mesangial cells acompanied with increase of endocapillary cells including neutrophils. Immunofluorescence microscopy showed granular deposits of C3 and IgA. Electron Microscopy revealed so-called "hump" on the subepithelial area. These features were consistent with the coexistence of IgA nephropathy (IgAN) and post-infectious glomerulonephritis. It is not clear about the prognosis and the therapeutic regimen in the patient who develop above situation. Although the patient showed still persistent proteinuria, high dose steroid therapy was probably useful for improving the disease.
