Normal Anagen Effluvium as the Presenting Sign of Pemphigus Vulgaris: a Case Report.
- Author:
You Jeong KIM
1
;
Mi Yeon KIM
;
Young Min PARK
;
Hyung Ok KIM
Author Information
1. Department of Dermatology, Kangnam St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. mykim@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Normal anagen effluvium;
Pemphigus vulgaris
- MeSH:
Autoantibodies;
Blister;
Desmosomes;
Epithelium;
Hair Follicle;
Humans;
Immunoglobulin G;
Mouth;
Mucous Membrane;
Pemphigus*;
Skin
- From:Korean Journal of Dermatology
2004;42(3):373-377
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membranes. It is characterized, histologically, by intraepidermal blisters, and immunopathologically, by the bound and circulating IgG directed to the epithelial desmosomes. In the majority of patients, painful mucous membrane erosions, especially in the oral cavity, are the presenting sign. The hair follicle is also a preferential target for pemphigus autoantibodies as the desmosomal proteins are overexpressed in follicular epithelium. We herein report a case of pemphigus vulgaris presenting with normal anagen effluvium.
