The Serogroup and Antimicrobial Resistance of Salmonella spp. Isolated from the Clinical Specimens During 6 years in a Tertiary University Hospital.
- Author:
Soyeon SEO
1
;
Mi Ae LEE
Author Information
1. Department of Laboratory Medicine, College of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea. miae@ewha.ac.kr
- Publication Type:Original Article
- Keywords:
Non-typhoidal Salmonellosis;
Serogroup;
Antimicrobial resistance;
Salmonella typhi
- MeSH:
Agar;
Ampicillin;
Ceftriaxone;
Ciprofloxacin;
Female;
Humans;
Salmonella Infections;
Salmonella typhi;
Salmonella*;
Selenious Acid;
Serotyping
- From:Korean Journal of Clinical Microbiology
2004;7(1):72-76
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Recently, non-typhoidal salmonellosis is increasing and it constituted over 90% of total salmonellosis in 1990s. The antimicrobial resistance of non-typhoidal Salmonella gets higher. So we described the change of serogroup and antimicrobial resistance of Salmonella isolated from clinical specimens in Ewha Womans University Mokdong Hospital during 6 years. METHODS: Clinical specimens were submitted from 1997 to 2002. Stool cultures were inoculated onto MacConkey (MAC) agar and Salmonella-Shigella (SS) agar and into Selenite F (SF) enrichment broth. Identification of Salmonella were performed by Vitek GNI card (BioMerieux, Marcy-I'Eltoile, France) and serotyping were done. Antimicrobial resistance test were performed by Vitek GNS card (BioMerieux, Marcy-I'Eltoile, France). RESULTS: From 1997 to 2002, 594 strains of Salmonella were isolated. Non-typhoidal Salmonella and Salmonella typhi constituted 94.4% and 5.6%. Non-typhoidal Salmonella were mainly composed of group B (21.5%) and group D (48.0%), but in 2002, group C (12.4%) and group E (27.9%) were increased in number. The antimicrobial resistance rate of non-typhpoidal Salmonella were 28% to ampicillin, 4.1% to SXT, 0.2% to ciprofloxacin and 0.7% to ceftriaxone. The animicrobial resistance rate of group B and D Salmonella showed 37.5% and 32.6% to ampicillin, 7.8% and 4.2% to SXT, respectively. CONCLUSIONS: Serogroup B and D Salmonella were most frequently isolated, but group C and E Salmonella have been increased in 2002. Antimicrobial resistance of group B and D Salmonella were higher than other serogroups and have been increased year by year.
