Five Cases of Glomuvenous Malformations.
- Author:
Hyun Jung LIM
1
;
Jae Hun JUN
;
Jae Chul LEE
;
Byung Soo KIM
;
Weon Ju LEE
;
Seok Jong LEE
;
Do Won KIM
;
Ho Yun CHUNG
;
Han Ik BAE
;
Jong Min LEE
Author Information
1. Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Glomus cell;
Glomuvenous malformation;
Venous malformation
- MeSH:
Blister;
Diagnosis, Differential;
Glomus Tumor;
Humans;
Paraganglioma, Extra-Adrenal;
Siblings;
Subcutaneous Tissue
- From:Korean Journal of Dermatology
2010;48(3):220-227
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Glomuvenous malformation (GVM), an uncommon variant of venous malformation (VM), reveals dilated venous channels lined by variable amounts of glomus cells histopathologically. It appears as compressible blue or blue-purple nodules or plaque(s), sometimes showing a familial tendency. GVM usually involves only the superficial layer of the cutis or subcutaneous tissue, unlike VM, which frequently involves deeper tissue. Although GVM shares features of VM and glomus tumor, their clinicopathological and/or genetic features are sufficiently distinctive to enable a differential diagnosis, which is important for management decisions. Herein, we report five patients who showed a large confluent patch or several scattered patches composed of tender bluish blebs. Two patients among them were siblings. Histopathological and immunohistochemical examinations confirmed GVM.
