A Case of Systemic Lupus Erythematous Associated with Neuromyelitis Optica (Devic's Syndrome).
10.4078/jkra.2007.14.3.263
- Author:
Pyung Chun OH
1
;
Geum Ha KIM
;
Choi Hyo JIN
;
Han Joo BAEK
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea. hjsalom@hanmail.net
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematous;
Neuromyelitis optica;
Devic's syndrome
- MeSH:
Adolescent;
Adult;
Cyclophosphamide;
Demyelinating Diseases;
Foot;
Humans;
Lupus Nephritis;
Magnetic Resonance Imaging;
Myelitis;
Neurologic Manifestations;
Neuromyelitis Optica*;
Optic Neuritis;
Paresthesia;
Prednisolone;
Rheumatology
- From:The Journal of the Korean Rheumatism Association
2007;14(3):263-267
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease, characterized by optic neuritis and myelitis. NMO is a very uncommon and serious neurologic manifestation of systemic lupus erythematous (SLE). We report a 28-year-old man with NMO as neuropsychiatric manifestation of SLE. He was diagnosed as lupus nephritis at 16-year-old. He had optic neuritis at three years and seven months ago. Oral prednisolone was tapered off according to the improved eye symptoms. Two months later, he visited rheumatology clinics for urinary disturbance and paresthesia on both feet. A spinal magnetic resonance imaging revealed increased signal intensity in T2-weighted images from second to sixth cervical level and from eleventh to twelfth thoracic level. We diagnosed neuromyelitis optica and treated with intravenous cyclophosphamide therapy monthly for three times. He was discharged without any neurological deficits and has been followed up.
