Dilated Cardiomyopathy Associated with Clozapine.
- Author:
Sungwon ROH
1
;
Dong Hyun AHN
;
Yang Suk KIM
;
Bang Hun LEE
Author Information
1. Department of Neuropsychiatry, College of Medicine, Hanyang University, Seoul, Korea. ahndh@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Clozapine;
Dilated cardiomyopathy
- MeSH:
Adult;
Agranulocytosis;
Antipsychotic Agents;
Cardiomyopathy, Dilated*;
Clozapine*;
Humans;
Korea;
Male;
Schizophrenia
- From:Journal of Korean Neuropsychiatric Association
2005;44(1):125-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clozapine is an atypical antipsychotic agent that is more effective than the typical neuroleptics in the treatment of refractory schizophrenia. However, clozapine is also a drug associated with potentially serious adverse effects, such as cardiac complications as well as agranulocytosis. Clozapine-related agranulocytosis has been reported in Korea, whereas clozapine-related cardiac complications have not. We report a 31-year-old male schizophrenia treated with clozapine who developed a dilated cardiomyopathy. We also reviewed literatures on dilated cardiomyopathy associated with clozapine treatment. This report is an attempt to raise the awareness of clozapine-related cardiac complications.
