The Effect of Inhalation Anesthetics on Platelet Function.
10.4097/kjae.1990.23.2.284
- Author:
Youn Woo LEE
1
;
Soo Yeoun KIM
;
Jong Rae KIM
;
Young Sun SEO
;
Kyung Soon SONG
Author Information
1. Department of Anesthesiology, Yongdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Enflurane;
Halothane;
Platelet function
- MeSH:
Adenosine Diphosphate;
Anesthesia;
Anesthesia, Inhalation;
Anesthetics, Inhalation*;
Blood Platelets*;
Collagen;
Enflurane;
Epinephrine;
Halothane;
Humans;
Inhalation*;
Ristocetin
- From:Korean Journal of Anesthesiology
1990;23(2):284-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
There is some controversy regarding the effect of general inhalation anesthesia on platelet function. In 20 patients undergoing long operations over 3 hours, and anesthetized with either nitrous oxide-oxygen and enflurane (A group) or nitrous oxide-oxygen and halothane (B group), we could not find any clinically significant impairment of coagulation. Platelet functions were consecutively evaluated on the samples collected at preinduction, during anesthesia (3 hours) and at postoperation (24 hours) using an aggregometer and several aggregating agents including ADP, epinephrine, collagen and ristocetin. There were no statistically significant changes between the maximum aggregation rate of preinduction and that duirng anesthesia in either group.
