Pathologic Features of Lacrimal Sac Mucosa in Primary Acquired Nasolacrimal Duct Obstruction Patients.
- Author:
Sang Hun LEE
1
;
Helen LEW
;
Jung Yun SIM
Author Information
1. Department of Ophthalmology, Pochun CHA University College of Medicine, Pundang CHA Hospital, Sungnam, Korea. eye@cha.ac.kr
- Publication Type:Original Article
- Keywords:
Dacryocystography;
Dacryocystorhinostomy;
Goblet cells;
Lacrimal sac;
Nasolacrimal duct obstruction;
Squamous metaplasia
- MeSH:
Dacryocystorhinostomy;
Demography;
Fibrosis;
Goblet Cells;
Humans;
Medical Records;
Mucous Membrane*;
Nasolacrimal Duct*
- From:Journal of the Korean Ophthalmological Society
2004;45(2):173-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study is to find out the relationship between clinical characteristics and pathologic findings of lacrimal sac in patients of primary acquired nasolacrimal duct obstruction. METHODS: This study reviewed medical records of 23 eyes of 21 patients who were received external dacryocystorhinostomy, and analyzed patients according to the obstruction patterns and locations on dacryocystography. The relationship between the pathologic degrees of lacrimal sac (inflammation, fibrosis, presence of goblet cells and squamous metaplasia) and clinical characteristics of the patients, was also evaluated. RESULTS: There were no significant relation between the pathologic degrees of lacrimal sac and clinical characteristics. From dacryocystography, the degree of fibrosis was 1.95 +/- 0.62 in complete obstruction, which was significantly higher than 1.00 +/- 0.82 in partial obstruction (p=0.015). In addition, the degree of fibrosis (2.20 +/- 0.63) was different depending on the location of the obstruction. In common canaliculus-obstruction group, it was 1.57 +/- 0.53 and in the nasolacrimal duct-obstruction group, it was 1.33 +/- 0.82 (p=0.041). However, there was no significant statistical difference between the patient's demographics and pathologic findings of lacrimal sac. CONCLUSIONS: The fibrosis of lacrimal sac mucosa is a major pathological finding of nasolacrimal duct obstruction and in particular, it is the characteristic of patients with lacrimal sac obstruction.
