A Case of Hemolytic Disease of Newborn Caused by Anti=hr'(c).
- Author:
Kyung Hee LEE
;
Hyung Woo KIM
;
Man Chul PARK
;
Yong Woo LEE
- Publication Type:Case Report
- Keywords:
Immune hemoytic anemia;
Minor blood group incompatibility;
Anti-c isoimmunization
- MeSH:
Anemia, Hemolytic;
Apnea;
Blood Group Antigens;
Cesarean Section;
Coombs Test;
Erythroblastosis, Fetal*;
Female;
Humans;
Immunoglobulin G;
Infant, Newborn;
Jaundice;
Mass Screening;
Mothers;
Pregnancy
- From:Korean Journal of Perinatology
1998;9(4):425-428
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Generally, the hemolytic disease of newborn caused by anti-c is characterized by the abnormal titer of anti-c in mother's serum and neonatal progressive jaundice caused by IgG induced hemolytic anemia. A female neonate delivered by cesarean section was admitted to Hangang Sacred Hospital due to severe jaundice and apnea on Jul. 7 1998. On admission, laboratory work up was revealed immune hemolytic anemia, but no incompatibility of ABO and Rh(D) system between mother and baby. Minor blood groups of mother and this second baby was ce and Cce. The serologic examination showed positive direct and indirect Coombs' test and the cause of jaundice was proved as the result of hemolytic disease due to anti-c via antibody screening and identification. After 2 times of exchange transfusion, the jaundice was subsided. So we reported a case of hemolytic disease due to anti-c with review of previous literatures.
