Prediction of Nodal Metastasis by the AMES Scoring System in Patients with Papillary Thyroid Cancer.
10.16956/kjes.2015.15.4.86
- Author:
Youn Ju LEE
1
;
Je Ryong KIM
Author Information
1. Department of Surgery, Chungnam National University School of Medicine, Daejeon, Korea. kimjr@cnuh.co.kr
- Publication Type:Original Article
- Keywords:
Papillary thyroid carcinoma;
Central lymph node;
AMES;
Lymph node metastasis;
Positron emission tomography-computed tomography
- MeSH:
Chungcheongnam-do;
Humans;
Multivariate Analysis;
Neoplasm Metastasis*;
Positron-Emission Tomography and Computed Tomography;
Tertiary Care Centers;
Thyroid Gland*;
Thyroid Neoplasms*;
Thyroidectomy
- From:Korean Journal of Endocrine Surgery
2015;15(4):86-92
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We assessed the prognostic value of AMES to determine the extent of surgery in PTC patients, and compared AMES score usefulness and accuracy with [18F] FDG PET/CT. METHODS: We conducted a review of data from a single center and a single surgeon, who treated 341 patients with PTC with total thyroidectomy and prophylactic bilateral CLN dissection at a tertiary referral center, Chungnam National University Hospital, between 2001 and 2012. RESULTS: In multivariate analysis, the rate of CLN metastasis was considerably higher in PTC patients with the higher AMES score (odds ratio [OR], 1.718; 95% confidence interval [CI], 1.073~2.752), higher SUV of the CLN (>0) (OR, 6.525; CI, 3.184~13.371), higher SUV of the tumor (>4.3) (OR, 1.855; CI, 1.065~3.231). CONCLUSION: The AMES score is helpful in deciding whether to perform a CLN dissection, as there is a strong association between the AMES score and CLN metastasis. This high predictive value of CLN metastasis can help determine the extent of PTC surgery while considering the cost and effort.
