Association between Paternal Age and Preterm Birth Based on Birth Certificate Data.
- Author:
Sang Hwa PARK
1
;
Seung Yup KU
;
Young Sik CHOI
;
Dong Won KIM
;
Shin Yong MOON
;
Seok Hyun KIM
Author Information
1. Institute of Reproductive Medicine and Population, Medical Research Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Preterm birth;
Birth certificate data;
Paternal age;
Risk factor
- MeSH:
Birth Certificates*;
Female;
Humans;
Incidence;
Infant;
Korea;
Logistic Models;
Odds Ratio;
Parturition*;
Paternal Age*;
Premature Birth*;
Risk Factors
- From:Korean Journal of Perinatology
2005;16(3):216-221
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To determine whether paternal age is associated with the risk of preterm birth. METHODS: Data were obtained from the 2003 birth certificates registry of 214,413 singleton infants born to women aged 25~29 years in Korea (Korea National Statistical Office). Odds ratios and 95% confidence intervals were calculated from multivariate logistic regression analyses to investigate the associations between paternal age and preterm delivery. RESULTS: The incidence of preterm birth showed a significant difference among the different paternal age groups (p<0.01). 'U-shaped' distribution of preterm birth risk was observed in terms of paternal age, with that of 30~34 years group being the lowest. Compared with 30~34 years group, the odds ratios for preterm birth were 1.14 for <24 years (p>0.05), 1.08 for age 25~29 years (p<0.01), 1.20 for age 35~39 years (p<0.01), and 1.50 for > or =40 years (p<0.01) groups. CONCLUSION: Paternal age is a risk factor for preterm birth and advanced paternal age increases the risk of preterm birth.