Chest Wall Pain as the Presenting Symptom of Leptomeningeal Carcinomatosis.
10.5535/arm.2014.38.6.861
- Author:
Kyoung Bo SIM
1
;
Ki Yeun NAM
;
Ho Jun LEE
;
Jin Woo PARK
;
Gi Hyeong RYU
;
Jihea CHANG
;
Bum Sun KWON
Author Information
1. Department of Physical Medicine and Rehabilitation, Dongguk University College of Medicine, Seoul, Korea. rusl98@hanmail.net
- Publication Type:Case Report
- Keywords:
Meningeal carcinomatosis;
Neoplasm metastasis;
Chest pain;
Lung cancer;
Leptomeningeal metastasis
- MeSH:
Adenocarcinoma;
Biopsy;
Breast Neoplasms;
Cerebrospinal Fluid;
Chest Pain;
Diagnosis;
Humans;
Lung;
Lung Neoplasms;
Melanoma;
Meningeal Carcinomatosis*;
Neoplasm Metastasis;
Thoracic Wall*;
Thorax
- From:Annals of Rehabilitation Medicine
2014;38(6):861-864
- CountryRepublic of Korea
- Language:English
-
Abstract:
Leptomeningeal metastasis (LMM), also referred to as leptomeningeal carcinomatosis, results from diffuse infiltration of the leptomeninges by malignant cells originating from extra-meningeal primary tumors. It occurs in approximately 5%-10% of patients with solid tumor. Among solid tumors, the most common types leading to infiltration of the leptomeninges are breast cancer, lung cancer, and melanoma. Patients with LMM may present various signs and symptoms. Herein, we report a rare case with initial presentation of isolated chest wall pain. Computed tomography of the chest with contrast revealed a 2.5-cm nodule over the left upper lung. Biopsy confirmed the diagnosis of adenocarcinoma. Later, cerebrospinal fluid cytology exam also confirmed leptomeningeal seeding. It is rare for leptomeningeal carcinomatosis patients to present with chest wall pain. Therefore, a high index of suspicion is mandatory for accurate and prompt diagnosis.
