On the Activity of MC3T3-E1 Cell in vitro.
- Author:
You Sung CHOI
1
;
Sang Chull LEE
Author Information
1. Department of Oral & Maxillofacial Surgery, College of Dentistry, Kyung-Hee University.
- Publication Type:In Vitro ; Original Article
- Keywords:
Ultrasound;
MC3T3-E1 cell;
Bone regeneration
- MeSH:
Acceleration;
Alkaline Phosphatase;
Bone Regeneration;
Cell Proliferation;
Fractures, Bone;
Osteoblasts;
Ultrasonography
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2001;27(2):103-110
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was performed to observe the effect of ultrasound(1.0MHz, 0.75W/cm2 and 1.0W/cm2) irradiation on cultured MC3T3-E1 cell, osteoblastic like cell with respect to the proliferation, protein synthesis, and alkaline phosphatase activity of the cells. The results were as follows: 1. The proliferation of MC3T3-E1 cells was increased on ultrasound irradiated group compared with control group. 2. The protein synthesis was not apparently increased on ultrasound irradiated group compared with control group. 3. The alkaline phosphatase activity level was not apparently increased on ultrasound irradiated group compared with control group. From the above results and other literatures, we could suggest that the ultrasound with the appropriate intensity and frequency may have important roles in stimulation of cell proliferation. Therefore the ultrasound may be used in the acceleration of the bone regeneration and bone fracture healing.
