Radioactive Iodine-Induced Graves' Disease in a Patient with Toxic Adenoma.
- Author:
Seokyoung YOON
1
;
Kichul SHIN
;
Eirie CHO
;
Min Joo KIM
Author Information
- Publication Type:Case Report
- Keywords: Graves' disease; Radioisotopes; Thyroid nodule; Thyrotoxicosis
- MeSH: Adenoma*; Adult; Antibodies; Diarrhea; Female; Graves Disease*; Humans; Iodine; Neck; Radioisotopes; Thyroid Gland; Thyroid Nodule; Thyrotoxicosis; Thyrotropin; Weight Loss
- From:Journal of Korean Thyroid Association 2015;8(1):98-102
- CountryRepublic of Korea
- Language:Korean
- Abstract: We report a rare case of radioactive iodine (RAI)-induced Graves' disease in a patient with toxic adenoma. A 42-year-old woman presented with neck masses. A hot nodule was detected on a thyroid scan, which suggested toxic adenoma. She was treated with RAI. Three months after the treatment, she complained of thyrotoxic symptoms such as weight loss, palpitation, diarrhea, and menstrual irregularity. A new thyroid scan showed diffuse increased uptake, while the toxic adenoma previously detected was now a cold nodule. Moreover, an increased level of antibodies against the thyroid-stimulating hormone receptor was detected. These findings indicated Graves' disease. Hence she was treated with anti-thyroid drug. This case serves as a reminder for physicians to consider RAI-induced Graves' disease if thyrotoxicosis is noted after RAI treatment.
