Change in the mGC-IPL in Patients with a History of APAC According to SD-OCT.
10.3341/jkos.2014.55.8.1167
- Author:
Hyo Seok LEE
1
;
Yong Seok PARK
;
Sang Woo PARK
Author Information
1. Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea. exo70@naver.com
- Publication Type:Original Article
- Keywords:
Acute primary angle closure;
Ganglion cell-inner plexiform layer
- MeSH:
Follow-Up Studies;
Ganglion Cysts;
Humans;
Intraocular Pressure;
Medical Records;
Nerve Fibers;
Retinaldehyde;
Retrospective Studies;
Tomography, Optical Coherence;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2014;55(8):1167-1173
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was conducted to measure macular ganglion cell-inner plexiform layer (mGC-IPL) thickness in patients with a history of unilateral single attack of acute primary angle closure (APAC) and to compare it with that of unaffected fellow eyes 8 weeks after resolution using spectrum domain optical coherence tomography (SD-OCT). METHODS: Medical records of 24 patients with history of first episode of unilateral APAC were reviewed retrospectively. Eight weeks after APAC, mGC-IPL thickness and peripapillary retinal nerve fiber layer thickness were measured with SD-OCT and analyzed in eyes affected by APAC (group 1) and fellow eyes (group 2). RESULTS: There were no significant differences between the groups with regard to best corrected visual acuity, spherical equivalent, central corneal thickness, or axial length (p > 0.05). There were no significant differences in mGC-IPL thickness in the superotemporal, superior, or superonasal sectors (p > 0.05). However, average, inferonasal, inferior, and inferotemporal sectors of group 1 were significantly thinner than those of group 2 (p = 0.002, 0.002, 0.001, 0.001, respectively). In addition, average mGC-IPL difference between affected eyes and fellow eyes showed a statistically significant correlation with attack duration (correlation coefficient = 0.249, p = 0.019). CONCLUSIONS: Normalization of elevated intraocular pressure as soon as possible after APAC onset is recommended in order to reduce mGC-IPL loss, and measurements of mGC-IPL thickness can be helpful for follow-up of APAC patients.
