Knowledge and Perception about Clinical Research Shapes Behavior: Face to Face Survey in Korean General Public.
10.3346/jkms.2016.31.5.674
- Author:
Yun Jung CHOI
1
;
Sung Ho BECK
;
Woon Yong KANG
;
Soyoung YOO
;
Seong Yoon KIM
;
Ji Sung LEE
;
Tal BURT
;
Tae Won KIM
Author Information
1. Asan Medical Center, Clinical Trial Center, Seoul, Korea. twkimmd@amc.seoul.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Clinical Research Perception;
Clinical Trial Participation;
Perception of Clinical Trial;
Awareness of Clinical Trial;
Patient Enrollment
- MeSH:
Adult;
Aged;
Awareness;
*Biomedical Research;
Clinical Trials as Topic;
Demography;
Female;
*Health Knowledge, Attitudes, Practice;
Humans;
India;
Interviews as Topic;
Male;
Middle Aged;
*Perception;
Republic of Korea;
Surveys and Questionnaires;
Young Adult
- From:Journal of Korean Medical Science
2016;31(5):674-681
- CountryRepublic of Korea
- Language:English
-
Abstract:
Considering general public as potential patients, identifying factors that hinder public participation poses great importance, especially in a research environment where demands for clinical trial participants outpace the supply. Hence, the aim of this study was to evaluate knowledge and perception about clinical research in general public. A total of 400 Seoul residents with no previous experience of clinical trial participation were selected, as representative of population in Seoul in terms of age and sex. To minimize selection bias, every fifth passer-by was invited to interview, and if in a cluster, person on the very right side was asked. To ensure the uniform use of survey, written instructions have been added to the questionnaire. Followed by pilot test in 40 subjects, the survey was administered face-to-face in December 2014. To investigate how perception shapes behavior, we compared perception scores in those who expressed willingness to participate and those who did not. Remarkably higher percentage of responders stated that they have heard of clinical research, and knew someone who participated (both, P < 0.001) compared to India. Yet, the percentage of responders expressed willingness to participate was 39.3%, a significantly lower rate than the result of the India (58.9% vs. 39.3%, P < 0.001). Treatment benefit was the single most influential reason for participation, followed by financial gain. Concern about safety was the main reason for refusal, succeeded by fear and lack of trust. Public awareness and educational programs addressing these negative perceptions and lack of knowledge will be effective in enhancing public engaged in clinical research.