Translation and Validation of a Korean Version of the Xerostomia Inventory in Patients with Primary Sjögren's Syndrome.
10.3346/jkms.2016.31.5.724
- Author:
Jennifer LEE
1
;
Jung Hee KOH
;
Seung Ki KWOK
;
Sung Hwan PARK
Author Information
1. Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea. rapark@catholic.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Xerostomia Inventory;
Sjögren's Syndrome, Cross-Cultural Adaptation
- MeSH:
Aged;
Asian Continental Ancestry Group;
Cohort Studies;
Female;
Humans;
Male;
Middle Aged;
Prospective Studies;
Reproducibility of Results;
Republic of Korea;
Salivary Glands/physiology;
Sjogren's Syndrome/*diagnosis/physiopathology;
Surveys and Questionnaires;
Translating;
Xerostomia/*diagnosis/physiopathology
- From:Journal of Korean Medical Science
2016;31(5):724-728
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study was conducted to generate and validate a cross-culturally adapted Korean version of the xerostomia inventory (XI), an 11-item questionnaire designed to measure the severity of xerostomia. The original English version of the XI was translated into Korean according to the guidelines for cross-cultural adaptation of health-related quality-of-life measures. Among a prospective cohort of primary Sjögren's syndrome (pSS) in Korea, 194 patients were analyzed. Internal consistency was evaluated by using Cronbach's alpha, and test-retest reliability was obtained by using an intraclass correlation coefficient (ICC) analysis. Construct validity was investigated by performing a correlation analysis between XI total score and salivary flow rate (SFR). Cronbach's alpha for internal consistency was 0.868, and the ICC for test-retest reliability ranged from 0.48 to 0.827, with a median value of 0.72. Moderate negative correlations between XI score and stimulated SFR, unstimulated SFR, and differential (stimulated minus unstimulated) SFR were observed (Spearman's rho, ρ = -0.515, -0.447, and -0.482, respectively; P < 0.001). The correlation analysis between the visual analogue scale (VAS) score of overall dryness and SFR indicated a smaller ρ value (-0.235 [P = 0.006], -0.243 [P = 0.002], and -0.252 [P = 0.003], respectively), which supports that XI more accurately reflects the degree of xerostomia in the pSS patients. In conclusion, the Korean version of the XI is a reliable tool to estimate the severity of xerostomia in patients with pSS.
