Review of Cohort Studies for Mood Disorders.
- Author:
Hong Jin JEON
1
;
Ji Hyun BAEK
;
Yong Min AHN
;
Se Joo KIM
;
Tae Hyun HA
;
Boseok CHA
;
Eunsoo MOON
;
Hee Ju KANG
;
Vin RYU
;
Chul Hyun CHO
;
Jung Yoon HEO
;
Kiwon KIM
;
Heon Jeong LEE
Author Information
- Publication Type:Review
- Keywords: Cohort study; Mood disorder; Bipolar disorder; Major depressive disorder; Review
- MeSH: Bipolar Disorder; Cohort Studies*; Depressive Disorder, Major; Follow-Up Studies; Humans; Mood Disorders*; Translational Medical Research
- From:Psychiatry Investigation 2016;13(3):265-276
- CountryRepublic of Korea
- Language:English
- Abstract: This paper aimed to review currently available cohort studies of subjects with mood disorders such as major depressive disorder (MDD) and bipolar disorder (BD). Using the PubMed and KoreaMed databases, we reviewed eight major cohort studies. Most studies recruited participants with MDD and BD separately, so direct comparison of factors associated with diagnostic changes was difficult. Regular and frequent follow-up evaluations utilizing objective mood ratings and standardized evaluation methods in a naturalistic fashion are necessary to determine detailed clinical courses of mood disorders. Further, biological samples should also be collected to incorporate clinical findings in the development of new diagnostic and therapeutic approaches. An innovative cohort study that can serve as a platform for translational research for treatment and prevention of mood disorders is critical in determining clinical, psychosocial, neurobiological and genetic factors associated with long-term courses and consequences of mood disorders in Korean patients.
