Evaluation of Platelet Concentrates Stored in the Second Generation Platelet Storage Containers.
- Author:
Dong Seok JEON
1
;
Gui Jeon CHOI
;
Young Woo JANG
;
Hyo Jin CHUN
;
Jae Ryong KIM
;
Dal Hyo SONG
Author Information
1. Department of Clinical Pathology, Keimyung University, College of Medicine, Taegu and Kyungpook Red Cross Blood Center*, Taegu, Korea.
- Publication Type:In Vitro ; Original Article
- Keywords:
Second generation platelet storage container Tri(2-ethylhexyl)trimellitate
- MeSH:
Blood Platelets*;
Humans;
Hydrogen-Ion Concentration;
Korea;
Mean Platelet Volume;
Plastics;
Platelet Aggregation;
Platelet Count
- From:Korean Journal of Blood Transfusion
1997;8(1):49-57
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Platelets can be stored for 3days at 22degrees C in conventional plastic bags plasticizer with di-(2-ethylhexyl)phthalate(DEHP). However, with such a short interval for storage, platelets could not be made easily available for thrombocytopenic patients. In vitro platelet function during 5 days of storage at 22degrees C was studied in a new plastic bag (second generation bag) which contained as plasticizer a tri (2-ethylhexyl)trimellitate and developed in Korea (Boin Medica Co.). METHODS: In vitro function (mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon) was evaluated in 20 units of platelet concentrate at day 0, 2, 5 while mixing in 60 rpm platelet rotator at 22degrees C. RESULTS: At day 5, platelet count, mean platelet volume, platelet distribution width, pH, platelet aggregation, platelet morphology and swirling phenomenon were well maintained. pO2, pCO2 and HCO3- were 65.6mmHg, 43.4mmHg and 12.3mmol/L at day 5, respectively. CONCLUSION: The data indicate that the use of the new platelet storage container will permit satisfactory storage for at least 5 days at 22degrees C.
