A Case of Clozapine-Induced Anemia and Thrombocytosis.
10.4306/jknpa.2015.54.2.252
- Author:
So Yeon JEON
1
;
Hanson PARK
Author Information
1. Department of Psychiatry, Seoul National University Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Clozapine;
Anemia;
Thrombocytosis;
Blood dyscrasia
- MeSH:
Agranulocytosis;
Anemia*;
Clozapine;
Neutropenia;
Platelet Count;
Thrombocytopenia;
Thrombocytosis*
- From:Journal of Korean Neuropsychiatric Association
2015;54(2):252-256
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clozapine is a well-known antipsychotic which causes hematologic adverse effects, specifically neutropenia and agranulocytosis (1-3% of patients). However, reports on blood dyscrasias like anemia and thrombocytosis after clozapine treatment are extremely rare. In some cases re-challenge of clozapine could lead to hematopoietic abnormality related to thrombocytopenia or thrombocytosis, which may be a result of an immune reaction. This case report suggests that clinicians should monitor platelet count after re-treatment with clozapine.
