A Case of Idiopathic Granulomatous Hypophysitis.
10.3904/kjim.2012.27.3.346
- Author:
Chul Ho CHUNG
1
;
Min Soo SONG
;
Hyun Deuk CHO
;
Du Shin JEONG
;
Yeo Joo KIM
;
Hack Gun BAE
;
Sang Jin KIM
Author Information
1. Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea. yeojoo@schch.co.kr
- Publication Type:Case Reports
- Keywords:
Granulomatous hypophysitis;
Headache;
Hypopituitarism
- MeSH:
Adult;
Biopsy;
Female;
Giant Cells/pathology;
Granuloma/complications/*diagnosis/therapy;
Headache/etiology;
Hemianopsia/etiology;
Humans;
Hyperprolactinemia/etiology;
Hypopituitarism/etiology;
Inflammation/complications/*diagnosis/therapy;
Magnetic Resonance Imaging;
Optic Chiasm/pathology;
Pituitary Diseases/complications/*diagnosis/therapy;
Pituitary Function Tests;
Pituitary Gland/*pathology/surgery;
Predictive Value of Tests;
Severity of Illness Index;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2012;27(3):346-349
- CountryRepublic of Korea
- Language:English
-
Abstract:
Granulomatous hypophysitis is a rare pituitary condition that commonly presents with enlargement of the pituitary gland. A 31-year-old woman was admitted to the hospital with a severe headache and bitemporal hemianopsia. Magnetic resonance imaging (MRI) showed an 18 x 10-mm sellar mass with suprasellar extension and compression of the optic chiasm. Interestingly, brain MRI had shown no abnormal finding 4 months previously. On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted. The biopsy revealed granulomatous changes with multinucleated giant cells. We herein report this rare case and discuss the relevant literature.