Simultaneous Occurrence of Hodgkin's Lymphoma and Langerhans Cell Histiocytosis of the Spine : A Rare Combination.
- Author:
Seung Jae HYUN
1
;
Seung Chul RHIM
;
Jooryung HUH
Author Information
1. Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hodgkin's disease;
Lymphoma;
Langerhans cell histiocytosis;
Spinal cord compression
- MeSH:
Histiocytosis, Langerhans-Cell;
Hodgkin Disease;
Humans;
Lower Extremity;
Lymphoma;
Middle Aged;
Spinal Cord Compression;
Spine;
Thoracic Vertebrae
- From:Journal of Korean Neurosurgical Society
2010;47(4):302-305
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hodgkin's disease presenting with spinal cord compression owing to extradural and bone involvement is extremely unusual. A 48-year-old man presented with progressive lower extremity weakness resulting from spinal cord compression attributable to an epidural mass in the thoracic vertebrae. The patient underwent decompressive surgery, and was then treated with chemotherapy for Langerhans cell histiocytosis. However, the disease progressed, and we performed second decompressive surgery with stabilization. Subsequent histopathological investigations revealed Hodgkin's lymphoma of the bone. Here, we describe an unusual case of spinal Hodgkin's lymphoma and Langerhans cell histiocytosis to draw attention to this combination as a possible diagnosis in patients with mixed inflammatory cell infiltrate lesions in the spine.
