The Role of Transient Receptor Potential Channel in Pain.
10.7599/hmr.2011.31.2.116
- Author:
Seung Jun JUNG
1
Author Information
1. Department of Physiology, Hanyang University College of Medicine, Seoul, Korea. eurijj@naver.com
- Publication Type:Review
- Keywords:
Pain;
Transient receptor potential channels;
Thermo-sensor;
Mechano-sensor;
Transducer
- MeSH:
Humans;
Nociception;
Proteins;
Sensation;
Transducers;
Transient Receptor Potential Channels
- From:Hanyang Medical Reviews
2011;31(2):116-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Transient receptor potential (TRP) channels, a large family of receptor channel proteins, initially attracted researchers in the pain field as key molecules in nociception, but later they became known as more general transducer molecules for various physical stresses. In this review, I will discuss their roles in thermal and mechanical sensation, and then consider their contribution to physiological pain.