A Case of Cytomegalovirus (CMV) Panniculitis after Renal Transplantation.
- Author:
Ho Sang BAE
1
;
Hyun Chaol LEE
;
Seung Hyea HYUN
;
Ji Young CHOI
;
Ja Yong PARK
;
Sung Won PARK
;
Chan Duck KIM
;
Sun Hee PARK
;
Yong Lim KIM
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea. ylkim@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Panniculitis;
Renal transplantation
- MeSH:
Biopsy;
Creatinine;
Cytomegalovirus*;
DNA;
Fever;
Ganciclovir;
Histiocytes;
Humans;
Kidney Transplantation*;
Middle Aged;
Panniculitis*;
Polymerase Chain Reaction;
Prednisone;
Recurrence;
Skin;
Suppuration;
Transplantation;
Transplants
- From:The Journal of the Korean Society for Transplantation
2005;19(2):215-218
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) remains an important pathogen in organ transplant patients. However, cutaneous lesions are rare manifestation of systemic CMV infection. We report a case of CMV panniculitis in a 47-year-old renal transplant recipient. She admitted due to fever, local pain in the left pelvic area, and erythematous tender palpable mass for 2 weeks. Twenty years ago, she underwent renal transplantation and had taken azathioprin 100 mg and prednisone 10 mg daily. Serum creatinine had been preserved between 2.5 and 3.5 mg/dL. Bacterial, fungal, and AFB cultures of skin lesion and drained pus were negative. CMV antigenemia was noted. Skin biopsy revealed multinucleated dermal histiocytes and positive for CMV antibody by immunohistochemical staining. Polymerase chain reaction testing of skin tissue and drained pus revealed CMV DNA. She was treated with ganciclovir for four weeks and skin lesion was completely resolved without recurrence.
