Can the Mean Platelet Volume Be a Risk Factor for Vasculogenic Erectile Dysfunction?.
10.5534/wjmh.2013.31.3.215
- Author:
Halil CIFTCI
1
;
Ercan YENI
;
Mehmet DEMIR
;
Ismail YAGMUR
;
Kemal GUMUS
;
Hakim CELIK
;
Murat SAVAS
;
Mehmet GULUM
Author Information
1. Department of Urology, Harran University Faculty of Medicine, Sanliurfa, Turkey. halilciftci63@hotmail.com
- Publication Type:Original Article
- Keywords:
Erectile dysfunction;
Impotence, vasculogenic;
Platelet
- MeSH:
Blood Platelets;
Diagnosis;
Disease Progression;
Erectile Dysfunction*;
Female;
Humans;
Impotence, Vasculogenic;
Male;
Mean Platelet Volume*;
Physical Examination;
Platelet Count;
Risk Factors*;
Ultrasonography, Doppler, Color;
Vascular Diseases
- From:The World Journal of Men's Health
2013;31(3):215-219
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The mean platelet volume (MPV) is a marker of the platelet activity and is reported to increase in vascular diseases. We aimed to investigate the association between MPV and vasculogenic erectile dysfunction (ED). MATERIALS AND METHODS: MPV and platelet (PLT) levels were measured in 50 cases of ED and 40 healthy controls. The diagnosis of vasculogenic ED was based on a detailed sexual history, physical examination, laboratory assessment, and color Doppler ultrasonography. The results are given as mean+/-standard deviation of the mean. RESULTS: The mean ages of the patient and the control groups were 53.70+/-12.39 years (range 24~77 years) and 53.85+/-9.5 years (range 30~73 years), respectively (p=0.947). The MPV and PLT values were significantly higher in the patients with ED than those of the controls (7.49+/-1.4), (6.85+/-1.2), (262.97+/-68), (252.89+/-82) respectively, p<0.001). However, the MPV values were not statistically significantly different in the patients with severe ED according to the International Index of Erectile Function than in those with mild ED, p>0.05), and there was no correlation between MPV and either age of patients (p=0.905) or duration of ED (p=0.583). CONCLUSIONS: The platelet count and MPV was detected to be increased in patients with vasculogenic ED. This finding suggests a role for platelets in the pathogenesis of vascular complications and that the MPV would be useful in monitoring disease progression.
