Dedifferentiated Liposarcoma with a Peculiar Whorling Pattern: A Case Report.
- Author:
Ji Shin LEE
1
;
Young Bog KIM
Author Information
1. Department of Pathology, Seonam Univerisy College of Medicine, Namwon, Korea. jshinlee@hanmail.net
- Publication Type:Case Report
- Keywords:
Liposarcoma, dedifferentiated
- MeSH:
Aged;
Humans;
Liposarcoma*;
Proliferating Cell Nuclear Antigen;
Sarcoma;
Scrotum
- From:Korean Journal of Pathology
2003;37(5):362-364
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A dedifferentiated liposarcoma is a uncommon neoplasm characterized by the coexistence of a well-differentiated liposarcoma and non-lipogenic sarcomas. A peculiar neural-like or meningothelial-like whorling pattern of dedifferentiation has recently been reported. We report a case of dedifferentiated liposarcoma with a peculiar whorling pattern in the scrotum of a 76-year-old man. Histologically, the tumor consisted of areas of a well differentiated liposarcoma admixed with areas of a morphologically non-lipogenic sarcoma. The whorls were scattered throughout the tumor. The cells in the whorls and dedifferentiated area showed a significant nuclear PCNA and p53 protein reactivity.
