Nephrotic syndrome complicated with portal, splenic, and superior mesenteric vein thrombosis.
10.1016/j.krcp.2014.07.001
- Author:
Bong Soo PARK
1
;
Sihyung PARK
;
Kyubok JIN
;
Gibok CHOI
;
Kang Min PARK
;
Kyeong Min JO
;
Yang Wook KIM
Author Information
1. Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. Kyw8625@chol.com
- Publication Type:Case Report
- Keywords:
Complications;
Nephrotic syndrome;
Thrombolytic therapy;
Venous thrombosis
- MeSH:
Follow-Up Studies;
Glomerulonephritis, Membranous;
Humans;
Incidence;
Mesenteric Veins*;
Nephrosis, Lipoid;
Nephrotic Syndrome*;
Portal Vein;
Renal Veins;
Splenic Vein;
Thromboembolism;
Thrombolytic Therapy;
Thrombosis*;
Urokinase-Type Plasminogen Activator;
Venous Thrombosis
- From:Kidney Research and Clinical Practice
2014;33(3):161-164
- CountryRepublic of Korea
- Language:English
-
Abstract:
Thromboembolism is a major complication of nephrotic syndrome. Renal vein thrombosis and deep vein thrombosis are relatively common, especially in membranous nephropathy. However, the incidence of portal vein and superior mesenteric vein (SMV) thrombosis in patients with nephrotic syndrome is very rare. To date, several cases of portal vein thrombosis treated by anticoagulation therapy, not by thrombolytic therapy, have been reported as a complication of nephrotic syndrome. Here, we report a case of portal, splenic, and SMV thrombosis in a patient with a relapsed steroid dependent minimal change disease who was treated successfully with anticoagulation and thrombolytic therapy using urokinase. Radiologic findings and his clinical conditions gradually improved. Six months later, a complete remission of the nephrotic syndrome was observed and the follow-up computed tomography scan showed the disappearance of all portal vein, splenic vein, and SMV thrombi.
