A cases of accident due to overdose of an antiarrhythmic 'propafenone
- Author:
Sinh Xuan Nguyen
- Publication Type:Journal Article
- Keywords:
propafenone
- MeSH:
Anti-Arrhythmia Agents;
Propafenone;
Overdose;
Accidents
- From:Journal of Vietnamese Medicine
1998;231(12):24-27
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Propafenone (Rythmonorm) was administered intravenously at a dose of 5mg/kg/3h to treat an atrial fibrillation case. Synal rhythm was restored in 2.30 hours with a QRS complex enlargement. 3 hours later on, a blood pressure drop as well as a cerebral and myocardial ischemia lasting 2 days were noted and were managed effectively with isoproterenol and dopamine. These drugs administered orally in divided doses up to 450 mg/day can put an end to the atrial fibrillation paroxysm while the maintenance dose of 450mg/day in fractional doses can prevent atrial fibrillation recurrence
