Multiple Attempts at Embryo Transfer do not Adversely Affect in-vitro Fertilization Pregnancy Rates: Related Mucus Contamination.
- Author:
Byeong Jun JUNG
1
;
Jong Sik KIM
;
Cheo Jin KWON
;
Mi Jin RYU
;
Myung Sin KIM
;
Eun Hee KANG
;
Jong Ok SIM
;
Hyun Jin SONG
;
Ik Hwan OH
Author Information
1. Department of Obstetrics and Gynecology, Seoul Women's Hospital, incheon, Korea. byeongjj@orgio.net
- Publication Type:Original Article
- Keywords:
Retained embryos;
Mucus contamination;
iVF-ET
- MeSH:
Catheters;
Embryo Transfer*;
Embryonic Structures*;
Female;
Fertilization*;
Humans;
Infertility;
Mucus*;
Pregnancy Rate*;
Pregnancy*
- From:Korean Journal of Fertility and Sterility
2003;30(1):57-64
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTiVE We investigate the effects of multiple attempts of embryo transfer because of retained embryos in the catheter and of contaminated mucus on the transferred catheter. MATERiALS AND METHODS: We respectively analysed data between November 1998 and August 2002 from 305 patients of 369 cycles who underwent iVF-ET. Of these patients, 47 patients of 50 cycles (Group 2) were required multiple trial of embryo transfer. They were compared with an age-matched control groups (Group 1) with female factor infertility. Pearson's c2 and Fisher's tests were used to compare proportions between discrete variables. Non-categorical data were compared using t-test. Statistical significance was set at p<0.05. RESULTS: Embryos were significantly more likely to be retained when catheter was contaminated with mucus (Group 1: 22.4%; Group 2: 44.0%). The clinical pregnancy rates, however, for the contaminated mucus or not, were 46.8%, 43.5% respectively. There was no significant difference clinical pregnancy rate between those who had all their embryos transferred at the first attempt (45.4%) and those who required more than one attempt (48.0%). CONCLUSiONS: Contaminated mucus in the catheter is associated with failed embryo transferred at the first attempt. Embryo transfers, however, that are repeated attempts do not adversely affect pregnancy rates following iVF-ET.
