Two Cases of Ethylene Glycol Poisoning.
- Author:
Jae Jin KIM
1
;
Sung Hyun YUN
;
Hyun Min JUNG
;
Ji Hye KIM
;
Seung Baik HAN
;
Jun Sig KIM
;
Jin Hui PAIK
Author Information
1. Department of Emergency Medicine, College of Medicine, Inha University, Incheon, Korea. riven2ne@naver.com
- Publication Type:Case Report
- Keywords:
Ethylene Glycol;
Metabolic acidosis;
Anion gap;
Osmolar concentration;
Diagnosis
- MeSH:
Achievement;
Acid-Base Equilibrium;
Acidosis;
Alcohol Dehydrogenase;
Early Diagnosis;
Ethylene Glycol;
Ethylenes;
Osmolar Concentration;
Renal Dialysis
- From:Journal of The Korean Society of Clinical Toxicology
2013;11(1):36-40
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ethylene glycol poisoning is treated mainly by alcohol dehydrogenase inhibition therapy and hemodialysis. Early recognition and initiation of treatment is important because toxic metabolites increase over time by hepatic metabolism; however, there is no confirmative diagnostic tool in our clinical setting. Therefore, diagnosis is dependent on history, high anion gap acidosis, high osmolal gap, etc.. Diagnosis and treatment are delayed in cases where history taking is not possible, such as a mental changed patient. Authors report on two cases of ethylene glycol poisoning by contrasting clinical outcomes, demonstrating the importance of early diagnosis and treatment for achievement of a good outcome.
