Systemic Factors Associated with Central Serous Chorioretinopathy in Koreans.
10.3341/kjo.2012.26.4.260
- Author:
Youngsub EOM
1
;
Jaeryung OH
;
Seong Woo KIM
;
Kuhl HUH
Author Information
1. Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. ojr4991@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Central serous chorioretinopathy;
Fatigue, Medicinal plants;
Sleep;
Snoring
- MeSH:
Asian Continental Ancestry Group;
Case-Control Studies;
Central Serous Chorioretinopathy/*epidemiology/*etiology;
Female;
Humans;
Logistic Models;
Male;
Middle Aged;
Questionnaires;
Republic of Korea/epidemiology;
Retrospective Studies;
Risk Factors;
Statistics, Nonparametric
- From:Korean Journal of Ophthalmology
2012;26(4):260-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To investigate systemic factors associated with central serous chorioretinopathy (CSC). METHODS: We retrospectively reviewed the medical records of 113 Korean patients who were diagnosed with CSC and who underwent history taking with a specialized questionnaire for CSC. They were matched for age and gender at a ratio of 1 : 3 to 339 normal controls. Normal controls were consecutively selected from a database at the Health Promotion Center. General characteristics and medical histories were compared between the two groups. The statistical analyses used included independent t-test, Mann-Whitney test, Fisher's exact test, and multivariate logistic regression analysis. RESULTS: There were 90 men and 23 women in the CSC group, and the male-female ratio for both groups was 3.9 : 1. The mean age of the patients was 45.6 years. In multivariate analysis, hypertension (odds ratio [OR], 2.327; 95% confidence interval [CI], 1.349-4.013), use of medicinal plants (OR, 2.198; 95% CI, 1.193-4.049), sleep disturbances (OR, 1.732; 95% CI, 1.096-2.739), and snoring (OR, 1.727; 95% CI, 1.058-2.820) were strongly associated with CSC. CONCLUSIONS: Hypertension, sleep disturbance, snoring, and medicinal plant use were identified as factors associated with CSC. Expanded history taking, including systemic factors and culture-specific behavior related to stress or fatigue such as use of medicinal plants, will be helpful in identifying Korean patients at an increased risk for CSC.
