A Case of Sequential Lymphoma in an Human Immunodeficiency Virus-Infected Patient.
10.3904/kjm.2015.88.4.469
- Author:
Yu Na JUNG
1
;
Jae Ryeong LEE
;
Hee Sook LEE
;
Bum Sik JIN
;
Chang In SEO
;
Hyoung Shik SHIN
;
Eun Jung JUNG
Author Information
1. Department of Internal Medicine, National Medical Center, Seoul, Korea. hyoungsshin@gmail.com
- Publication Type:Case Report
- Keywords:
Human immunodeficiency virus;
Hodgkin's lymphoma;
T-cell lymphoma
- MeSH:
Biopsy, Needle;
Bleomycin;
Dacarbazine;
Diagnosis;
Doxorubicin;
Drug Therapy;
Drug Therapy, Combination;
HIV;
Hodgkin Disease;
Humans;
Liver;
Lymphoma*;
Lymphoma, T-Cell;
Middle Aged;
Polymerase Chain Reaction;
Vinblastine
- From:Korean Journal of Medicine
2015;88(4):469-474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Rarely, two different histological types of lymphoma develop in the same person. Sequential lymphoma is defined as two different types of lymphoma occurring in the same person sequentially. A 47-year-old patient with human immunodeficiency virus (HIV) infection who had been diagnosed with mixed cellularity Hodgkin's lymphoma was treated with adriamycin, bleomycin, vinblastine, and dacarbazine combination chemotherapy. After six cycles of chemotherapy, abdominal computed tomography showed multiple liver masses. A percutaneous needle biopsy of the liver and polymerase chain reaction single-strand conformation polymorphism revealed hepatosplenic T-cell lymphoma. The patient died 3 months after the diagnosis of hepatosplenic T-cell lymphoma. To our knowledge, this is the first case of the sequential development of hepatosplenic T-cell lymphoma after Hodgkin's lymphoma in a Korean HIV-infected patient.
